The European Society of Gynaecological Oncology/European Society for Radiotherapy and Oncology/European Society of Pathology Guidelines for the Management of Patients with Cervical Cancer

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • David Cibula - , Charles University Prague (Author)
  • Richard Pötter - , Medical University of Vienna (Author)
  • François Planchamp - , Centre Georges-François Leclerc (Author)
  • Elisabeth Avall-Lundqvist - , Linköping University (Author)
  • Daniela Fischerova - , Charles University Prague (Author)
  • Christine Haie-Meder - , Institut Gustave Roussy (Author)
  • Christhardt Köhler - , University of Cologne (Author)
  • Fabio Landoni - , University of Milan - Bicocca (Author)
  • Sigurd Lax - , Hospital Graz II (Author)
  • Jacob Christian Lindegaard - , Aarhus University (Author)
  • Umesh Mahantshetty - , Tata Memorial Hospital (Author)
  • Patrice Mathevet - , University of Lausanne (Author)
  • W. Glenn McCluggage - , Belfast Health and Social Care Trust (Author)
  • Mary McCormack - , University College London (Author)
  • Raj Naik - , Gateshead Health NHS Foundation Trust (Author)
  • Remi Nout - , Leiden University (Author)
  • Sandro Pignata - , IRCCS Istituto nazionale tumori Fondazione Giovanni Pascale - Napoli (Author)
  • Jordi Ponce - , University of Barcelona (Author)
  • Denis Querleu - , Centre Georges-François Leclerc (Author)
  • Francesco Raspagliesi - , IRCCS Fondazione Istituto Nazionale per lo studio e la cura dei tumori - Milano (Author)
  • Alexandros Rodolakis - , National and Kapodistrian University of Athens (Author)
  • Karl Tamussino - , Medical University of Graz (Author)
  • Pauline Wimberger - , Department of Gynecology and Obstetrics (Author)
  • Maria Rosaria Raspollini - , Careggi University Hospital (Author)

Abstract

Background:: Despite significant advances in the screening, detection, and treatment of preinvasive cervical lesions, invasive cervical cancer is the fifth most common cancer in European women. There are large disparities in Europe and worldwide in the incidence, management, and mortality of cervical cancer. Objective:: The European Society of Gynecological Oncology (ESGO), the European Society for Radiotherapy and Oncology (ESTRO), and the European Society of Pathology (ESP) jointly develop clinically relevant and evidence-based guidelines in order to improve the quality of care for women with cervical cancer across Europe and worldwide. Methods:: The ESGO/ESTRO/ESP nominated an international multidisciplinary development group consisting of practicing clinicians and researchers who have demonstrated leadership and expertise in the care and research of cervical cancer (23 experts across Europe). To ensure that the guidelines are evidence based, the current literature identified from a systematic search was reviewed and critically appraised. In the absence of any clear scientific evidence, judgment was based on the professional experience and consensus of the development group. The guidelines are thus based on the best available evidence and expert agreement. Prior to publication, the guidelines were reviewed by 159 international reviewers, selected through ESGO/ESTRO/ESP and including patient representatives. Results:: The guidelines cover comprehensively staging, management, and follow-up for patients with cervical cancer. Management includes fertility sparing treatment; stage T1a, T1b1/T2a1, clinically occult cervical cancer diagnosed after simple hysterectomy; early and locally advanced cervical cancer; primary distant metastatic disease; cervical cancer in pregnancy; and recurrent disease. Principles of radiotherapy and pathological evaluation are defined.

Details

Original languageEnglish
Pages (from-to)919-936
Number of pages18
JournalVirchows Archiv
Volume472
Issue number6
Publication statusPublished - 1 Jun 2018
Peer-reviewedYes

External IDs

PubMed 29725757

Keywords

Sustainable Development Goals

Keywords

  • Cervical cancer, Follow-up, Guidelines, Management, Staging