The Collaborative Cross, a community resource for the genetic analysis of complex traits

Research output: Contribution to journal › Review article › Contributed › peer-review

Contributors

  • Gary A. Churchill - , Jackson Laboratory (Author)
  • David C. Airey - , Vanderbilt University (Author)
  • Hooman Allayee - , University of Southern California (Author)
  • Joe M. Angel - , University of Texas at Austin (Author)
  • Alan D. Attie - , University of Wisconsin-Madison (Author)
  • Jackson Beatty - , University of California at Los Angeles (Author)
  • Willam D. Beavis - , National Center for Genome Resources (Author)
  • John K. Belknap - , Portland VA Medical Center (Author)
  • Beth Bennett - , University of Colorado Boulder (Author)
  • Wade Berrettini - , University of Pennsylvania (Author)
  • Andre Bleich - , Hannover Medical School (MHH) (Author)
  • Molly Bogue - , Jackson Laboratory (Author)
  • Karl W. Broman - , Johns Hopkins University (Author)
  • Kari J. Buck - , Oregon Health and Science University (Author)
  • Ed Buckler - , Cornell University (Author)
  • Margit Burmeister - , University of Michigan, Ann Arbor (Author)
  • Elissa J. Chesler - , University of Tennessee Health Science Center (Author)
  • James M. Cheverud - , Washington University St. Louis (Author)
  • Steven Clapcote - , University of Toronto (Author)
  • Melloni N. Cook - , University of Memphis (Author)
  • Roger D. Cox - , Medical Research Council (MRC) (Author)
  • John C. Crabbe - , Oregon Health and Science University (Author)
  • Wim E. Crusio - , University of Massachusetts Medical School (Author)
  • Ariel Darvasi - , Hebrew University of Jerusalem (Author)
  • Christian F. Deschepper - , University of Montreal (Author)
  • R. W. Doerge - , Purdue University (Author)
  • Charles R. Farber - , University of California at Davis (Author)
  • Jiri Forejt - , Czech Academy of Sciences (Author)
  • Daniel Gaile - , State University of New York (SUNY) at Buffalo (Author)
  • Steven J. Garlow - , Emory University (Author)
  • Hartmut Geiger - , University of Cincinnati (Author)
  • Howard Gershenfeld - , University of Texas Southwestern Medical Center (Author)
  • Terry Gordon - , New York University (Author)
  • Jing Gu - , University of Tennessee Health Science Center (Author)
  • Weikuan Gu - , University of Tennessee Health Science Center (Author)
  • Gerald de Haan - , University of Groningen (Author)
  • Nancy L. Hayes - , Rutgers - The State University of New Jersey, New Brunswick (Author)
  • Craig Heller - , Stanford University (Author)
  • Heinz Himmelbauer - , Max Planck Institute for Molecular Genetics (Author)
  • Robert Hitzemann - , Oregon Health and Science University (Author)
  • Kent Hunter - , National Institutes of Health (NIH) (Author)
  • Hui Chen Hsu - , University of Alabama at Birmingham (Author)
  • Fuad A. Iraqi - , International Livestock Research Institute (Author)
  • Boris Ivandic - , Heidelberg University  (Author)
  • Howard J. Jacob - , Medical College of Wisconsin (Author)
  • Ritsert C. Jansen - , University of Groningen (Author)
  • Karl J. Jepsen - , Icahn School of Medicine at Mount Sinai (Author)
  • Dabney K. Johnson - , Oak Ridge National Laboratory (Author)
  • Thomas E. Johnson - , University of Colorado Boulder (Author)
  • Gerd Kempermann - , Charité – Universitätsmedizin Berlin (Author)

Abstract

The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.

Details

Original languageEnglish
Pages (from-to)1133-1137
Number of pages5
JournalNature genetics
Volume36
Issue number11
Publication statusPublished - Nov 2004
Peer-reviewedYes
Externally publishedYes

External IDs

PubMed 15514660
ORCID /0000-0002-5304-4061/work/152544221

Keywords

Sustainable Development Goals

ASJC Scopus subject areas