Testosteronmangel im Alter – was ist zu tun?

Research output: Contribution to journalResearch articleContributed

Contributors

Abstract

Over the past years, a growing demand for testosterone replacement therapy in aging men has been noted in the US as well as in Europe. The current evidence for detrimental consequences of low testosterone in old men is largely based on retrospective studies. On the other hand, prospective placebo-controlled randomized trials investigating clinically relevant endpoints are limited. Clinical benefits of testosterone replacement therapy in ageing men include improved sexual function and libido, increase in muscle mass and -function, as well as bone mass accrual. Whether testosterone supplementation in ageing men confers an altered risk for cardiovascular disease and/or prostate cancer remains unclear. Ongoing clinical trials (e. g. TRAVERSE trial, NCT03 518 034) will help to resolve these questions.

Translated title of the contribution
Testosterone deficiency in the ageing male

Details

Original languageGerman
Pages (from-to)141-145
Number of pages5
JournalDeutsche Medizinische Wochenschrift
Volume146
Issue number3
Publication statusPublished - Feb 2021
Peer-reviewedNo

External IDs

Scopus 85100459628
ORCID /0000-0002-8691-8423/work/142236031

Keywords

Sustainable Development Goals

Keywords

  • Adult, Aged, Aged, 80 and over, Aging/physiology, Cardiovascular Diseases, Humans, Male, Middle Aged, Prostatic Neoplasms, Randomized Controlled Trials as Topic, Retrospective Studies, Testosterone/blood

Library keywords