Sutureless Versus Rapid Deployment Aortic Valve Replacement: Results From a Multicenter Registry

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Paolo Berretta - , Marche Polytechnic University (Author)
  • Bart Meuris - , Cardiale Heelkunde (Author)
  • Utz Kappert - , TUD Dresden University of Technology (Author)
  • Martin Andreas - , Medical University of Vienna (Author)
  • Antonio Fiore - , Hôpital Henri Mondor (Author)
  • Marco Solinas - , Heart Hospital Pasquinucci Hospital of Massa (Author)
  • Martin Misfeld - , University Hospital Carl Gustav Carus Dresden (Author)
  • Thierry P Carrel - , Inselspital University Hospital Bern (Author)
  • Emmanuel Villa - , Poliambulanza Foundation Hospital (Author)
  • Carlo Savini - , University of Bologna (Author)
  • Giuseppe Santarpino - , Paracelsus Private Medical University (Author)
  • Kevin Teoh - , Southlake Regional Health Centre (Author)
  • Alberto Albertini - , Maria Cecilia Hospital (Author)
  • Theodor Fischlein - , Paracelsus Private Medical University (Author)
  • Gianluca Martinelli - , Cardiac Surgery Unit (Author)
  • Carmelo Mignosa - , Department for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation (Author)
  • Mattia Glauber - , Clinical & Research Hospitals Istituto di Ricovero e Cura a Carattere Scientifico Gruppo San Donato (Author)
  • Malak Shrestha - , Hannover Medical School (MHH) (Author)
  • Ghunter Laufer - , Medical University of Vienna (Author)
  • Kevin Phan - , The Collaborative Research (CORE) Group (Author)
  • Tristan Yan - , Royal Prince Alfred Hospital (Author)
  • Marco Di Eusanio - , Marche Polytechnic University (Author)

Abstract

BACKGROUND: This study compared clinical and hemodynamic in-hospital outcomes of patients undergoing sutureless vs rapid deployment aortic valve replacement (SURD-AVR) in the large population of the Sutureless and Rapid Deployment International Registry (SURD-IR).

METHODS: We examined 4695 patients who underwent isolated or combined SURD-AVR. The "sutureless" Perceval valve (LivaNova PLC, London, United Kingdom) was used in 3133 patients and the "rapid deployment" Intuity (Edwards Lifesciences, Irvine, CA) in 1562. Potential confounding factors were addressed by the use of propensity score matching. After matching, 2 well-balanced cohorts of 823 pairs (isolated SURD-AVR) and 467 pairs (combined SURD-AVR) were created.

RESULTS: Patients who received Perceval and Intuity valves showed similar in-hospital mortality and rate of major postoperative complications. Perceval was associated shorter cross-clamp and cardiopulmonary bypass times. In the isolated SURD-AVR group, patients receiving Perceval were more likely to undergo anterior right thoracotomy incision. Postoperative transvalvular gradients were significantly lower for the Intuity valve compared with those of the Perceval valve, either in isolated and combined SURD-AVR. The Intuity valve was associated with a lower rate of postoperative mild aortic regurgitation.

CONCLUSIONS: Our results confirm the safety and efficacy of SURD-AVR regardless of the valve type. The Perceval valve was associated with reduced operative times and increased anterior right thoracotomy incision. The Intuity valve showed superior hemodynamic outcomes and a lower incidence of postoperative mild aortic regurgitation.

Details

Original languageEnglish
Pages (from-to)758-765
Number of pages8
JournalThe annals of thoracic surgery
Volume114
Issue number3
Publication statusPublished - Sept 2022
Peer-reviewedYes
Externally publishedYes

External IDs

Scopus 85120794926

Keywords

Keywords

  • Aortic Valve/surgery, Aortic Valve Insufficiency/surgery, Aortic Valve Stenosis, Bioprosthesis, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation/methods, Humans, Prosthesis Design, Registries, Retrospective Studies, Treatment Outcome