Surrogate based continuous noninvasive blood pressure measurement

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Alexandru-Gabriel Pielmus - , Technical University of Berlin (Author)
  • Jens Mühlstef - , Philips Research Europe (Author)
  • Erik Bresch - , Philips Research Europe (Author)
  • Martin Glos - , Charité – Universitätsmedizin Berlin (Author)
  • Christiane Jungen - , University Hospital Hamburg Eppendorf (Author)
  • Stefan Mieke - , National Metrology Institute of Germany (PTB) (Author)
  • Reinhold Orglmeister - , Technical University of Berlin (Author)
  • Andreas Schulze - , Philips Research Europe (Author)
  • Birgit Stender - , Drägerwerk AG & Co. KGaA (Author)
  • Verena Voigt - , RWTH Aachen University (Author)
  • Sebastian Zaunseder - , Chair of Biomedical Engineering, Dortmund University of Applied Sciences and Arts (Author)

Abstract

Arterial blood pressure is one of the most often measured vital parameters in clinical practice. State-of-the-art noninvasive ABP measurement technologies have noticeable limitations and are mainly based on uncomfortable techniques of complete or partial arterial occlusion by cuffs. Most commonplace devices provide only intermittent measurements, and continuous systems are bulky and difficult to apply correctly for nonprofessionals. Continuous cuffless ABP measurements are still an unmet clinical need and a topic of ongoing research, with only few commercially available devices. This paper discusses surrogate-based noninvasive blood pressure measurement techniques. It covers measurement methods of continuously and noninvasively inferring BP from surrogate signals without applying external pressures, except for reference or initialization purposes. The BP is estimated by processing signal features, so called surrogates, which are modulated by variations of BP. Discussed techniques include well-known approaches such as pulse transit time and pulse arrival time techniques, pulse wave analysis or combinations thereof. Despite a long research history, these methods have not found widespread use in clinical and ambulatory practice, in part due to technical limitations and the lack of a standardized regulatory framework. This work summarizes findings from an invited workshop of experts in the fields covering clinical expertise, engineering aspects, commercialization and standardization issues. The goal is to provide an application driven outlook, starting with clinical needs, and extending to technical actuality. It provides an outline of recommended research directions and includes a detailed overview of clinical use case scenarios for these technologies, opportunities, and limitations.

Details

Original languageEnglish
Pages (from-to)231-245
Number of pages15
JournalBiomedizinische Technik
Volume66
Issue number3
Early online date10 Feb 2021
Publication statusPublished - 25 Jun 2021
Peer-reviewedYes

External IDs

Scopus 85100953065

Keywords

Research priority areas of TU Dresden

Subject groups, research areas, subject areas according to Destatis

Sustainable Development Goals

Keywords

  • NIBP, blood pressure, clinical, guideline, measurement, noninvasive, recommendation