Surface-conditioned dental implants: An animal study on bone formation

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Bernd Stadlinger - , TUD Dresden University of Technology (Author)
  • Anna Theresa Lode - , TUD Dresden University of Technology (Author)
  • Uwe Eckelt - , TUD Dresden University of Technology (Author)
  • Ursula Range - , TUD Dresden University of Technology (Author)
  • Falko Schlottig - , Thommen Medical AG (Author)
  • Thomas Hefti - , Thommen Medical AG (Author)
  • Ronald Mai - , TUD Dresden University of Technology (Author)

Abstract

Aim: The aim of this study was to determine whether bone formation around surface-conditioned implants is enhanced compared with non-surface-conditioned sandblasted acid-etched titanium implants. Materials and Methods: One hundred and forty-four implants were placed in the mandible of 18 minipigs. Before placement, implants were either surface conditioned in a solution containing hydroxide ions (conSF) or assigned to controls. Animals were euthanized after 2, 4 and 8 weeks of submerged healing, the 8-week group receiving polyfluorochrome labelling at week 2, 4, 6 and 8. One jaw quadrant per animal was selected for histological and histomorphometrical evaluation of mineralized bone-implant contact (mBIC), osteoid-implant contact (OIC) and bone volume (BV) analysis. Results: Polyfluorochrome labelling showed no general differences in bone dynamics. mBIC showed the most pronounced differences after 2 weeks, reaching 65.5% for conSF compared with 48.1% for controls, p=0.270. Differences levelled out after 4 weeks (67.4% control, 65.7% conSF) and 8 weeks (64.0% control, 70.2% conSF). OIC levels were initially comparable, showing a slower decline for conSF after 4 weeks. BV was higher for conSF at all times. No significant differences could be found. Conclusion: A tendency towards increased mBIC was shown for surface-conditioned implants after short-term healing.

Details

Original languageEnglish
Pages (from-to)882-891
Number of pages10
JournalJournal of clinical periodontology
Volume36
Issue number10
Publication statusPublished - Oct 2009
Peer-reviewedYes

External IDs

PubMed 19735467

Keywords

ASJC Scopus subject areas

Keywords

  • Conditioning, Dental implant, Histomorphometry, Osseointegration