Successful resuscitation following ropivacaine-induced systemic toxicity in a neonate

Research output: Contribution to journalResearch articleContributedpeer-review

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Abstract

A 5-week-old preterm infant was scheduled for inguinal hernia repair. Following induction of general anaesthesia, 10 mg.kg-1 ropivacaine was injected, accidently, into the caudal space. The infant developed cardiac depression with bradycardia (minimum heart rate 50 beats.min-1), elevated T waves and widening of QRS complexes. Resuscitation by means of external chest compression, intravenous adrenaline and fluid administration was successful. Ropivacaine serum concentrations were obtained at three time points yielding a peak level of 6 μg.ml-1 20 min after caudal injection.

Details

Original languageEnglish
Pages (from-to)1137-1140
Number of pages4
Journal Anaesthesia : the official journal of the Association of Anaesthesists of Great Britain and Ireland
Volume65
Issue number11
Publication statusPublished - Nov 2010
Peer-reviewedYes

External IDs

researchoutputwizard legacy.publication#36109
Scopus 78049505568
PubMed 20645946
ORCID /0000-0003-1526-997X/work/142247321

Keywords