Störungen der Chemosensorik bei Covid-19: Pathomechanismen und klinische Relevanz

Research output: Contribution to journalReview articleContributedpeer-review

Contributors

Abstract

In this review article, current information on the frequency and relevance of chemosensory disorders in Covid-19 was recorded, assigned pathophysiologically and statements on prognostic significance were derived. The results are based on a comprehensive literature search of all literature on this topic and our own experience in the treatment of patients with smell and taste disorders since the beginning of the pandemic.Current study results indicate that clinically less affected Covid-19 patients without inpatient treatment and who do not require ventilation often have disorders of the chemosensory system. In young patients and women in particular, they seem to be an indicator of a favorable prognosis for the course of the disease. Smell disorders can appear early, as the sole symptom or together with other symptoms of Covid-19 disease. It has not yet been clarified whether ageusia can occur independently or whether it is also felt in the context of anosmia. In the pandemic, the new occurrence of anosmia without congestion / obstruction/runny nose is probably an expression of an infection with SARS-CoV-2 and should always give rise to quarantine and testing for SARS-CoV-2. The smell disorder in Covid-19 mostly seems to be temporary; It is not yet possible to conclusively assess whether there is usually a full restitution. The therapeutic approaches already established for other postviral olfactory disorders (e. g. olfactory training) are also used here.

Translated title of the contribution
Chemosensory disorders in Covid-19
Pathomechanisms and clinical relevance

Details

Original languageGerman
Pages (from-to)281-288
Number of pages8
JournalFortschritte der Neurologie, Psychiatrie : FDN
Volume89
Issue number6
Publication statusPublished - Jun 2021
Peer-reviewedYes

External IDs

Scopus 85101684854
ORCID /0000-0001-9713-0183/work/146645311
ORCID /0000-0003-1311-8000/work/158767522

Keywords

Keywords

  • COVID-19, Female, Humans, Olfaction Disorders/epidemiology, Pandemics, SARS-CoV-2, Taste Disorders