Structure-integrated force measurement in hexapod structures or kinematics offers great potential for spatial process force control in six degrees of freedom. Although force control has been studied for many years, research questions remain unanswered, especially when regarding parallel kinematic machine tools with numerical control and integrated sensors. This contribution summarizes the technology of structure-integrated force sensing in hexapod machine tools and develops two approaches to use the measured signals for direct hybrid/parallel force control. For different use-cases, such as teach-in or synchronous force/position control with variable task frame, different approaches of set-point specification and injection of manipulated values are studied from a practical point of view. As a result of the work, the feasibility of the force control with structure-integrated sensors on a commercial CNC can be confirmed through appropriate experiments. Furthermore, the realized G-Code integration represents a practical solution for programming force-controlled machine tools in an easy and concise way from the NC programme.