Soft Listeria: Actin-based propulsion of liquid drops

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Hakim Boukellal - , Institut Curie (Author)
  • Otger Campás - , Institut Curie, University of Barcelona (Author)
  • Jean François Joanny - , Institut Curie (Author)
  • Jacques Prost - , Institut Curie (Author)
  • Cécile Sykes - , Institut Curie (Author)

Abstract

We study the motion of oil drops propelled by actin polymerization in cell extracts. Drops deform and acquire a pearlike shape under the action of the elastic stresses exerted by the actin comet, a tail of cross-linked actin filaments. We solve this free boundary problem and calculate the drop shape taking into account the elasticity of the actin gel and the variation of the polymerization velocity with normal stress. The pressure balance on the liquid drop imposes a zero propulsive force if gradients in surface tension or internal pressure are not taken into account. Quantitative parameters of actin polymerization are obtained by fitting theory to experiment.

Details

Original languageEnglish
Pages (from-to)4
Number of pages1
JournalPhysical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
Volume69
Issue number6
Publication statusPublished - 2004
Peer-reviewedYes
Externally publishedYes

External IDs

PubMed 15244616