Smart hydrogels as storage elements with dispensing functionality in discontinuous microfluidic systems

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

Abstract

Smart hydrogels are useful elements in microfluidic systems because they respond to environmental stimuli and are capable of storing reagents. We present here a concept of using hydrogels (poly(N-isopropylacrylamide)) as an interface between continuous and discontinuous microfluidics. Their swelling and shrinking capabilities allow them to act as storage elements for reagents absorbed in the swelling process. When the swollen hydrogel collapses in an oil-filled channel, the incorporated water and molecules are expelled from the hydrogel and form a water reservoir. Water-in-oil droplets can be released from the reservoir generating different sized droplets depending on the flow regime at various oil flow rates (dispensing functionality). Different hydrogel sizes and microfluidic structures are discussed in terms of their storage and droplet formation capabilities. The time behaviour of the hydrogel element is …

Details

Original languageEnglish
Pages (from-to)3977
Number of pages3989
JournalLab on a Chip
Publication statusPublished - 2016
Peer-reviewedYes

External IDs

Scopus 84990847717
ORCID /0000-0002-8588-9755/work/142246761

Keywords