Silicon-Vacancy Nanodiamonds as High Performance Near-Infrared Emitters for Live-Cell Dual-Color Imaging and Thermometry

Research output: Contribution to journal › Research article › Contributed › peer-review

Contributors

  • Weina Liu - , Max Planck Institute for Polymer Research, Ulm University, Swiss Federal Institute of Technology Lausanne (EPFL) (Author)
  • Md Noor A. Alam - , Max Planck Institute for Polymer Research, Ulm University (Author)
  • Yan Liu - , Beijing Academy of Quantum Information Sciences, Ulm University (Author)
  • Viatcheslav N. Agafonov - , Université de Tours (Author)
  • Haoyuan Qi - , Chair of Molecular Functional Materials (cfaed), Ulm University (Author)
  • Kaloian Koynov - , Max Planck Institute for Polymer Research (Author)
  • Valery A. Davydov - , Russian Academy of Sciences (Author)
  • Rustem Uzbekov - , Université de Tours, Lomonosov Moscow State University (Author)
  • Ute Kaiser - , Ulm University (Author)
  • Theo Lasser - , Max Planck Institute for Polymer Research (Author)
  • Fedor Jelezko - , Ulm University (Author)
  • Anna Ermakova - , Max Planck Institute for Polymer Research, Johannes Gutenberg University Mainz (Author)
  • Tanja Weil - , Max Planck Institute for Polymer Research, Ulm University (Author)

Abstract

Nanodiamonds (NDs) with color centers are excellent emitters for various bioimaging and quantum biosensing applications. In our work, we explore new applications of NDs with silicon-vacancy centers (SiV) obtained by high-pressure high-Temperature (HPHT) synthesis based on metal-catalyst-free growth. They are coated with a polypeptide biopolymer, which is essential for efficient cellular uptake. The unique optical properties of NDs with SiV are their high photostability and narrow emission in the near-infrared region. Our results demonstrate for the first time that NDs with SiV allow live-cell dual-color imaging and intracellular tracking. Also, intracellular thermometry and challenges associated with SiV atomic defects in NDs are investigated and discussed for the first time. NDs with SiV nanoemitters provide new avenues for live-cell bioimaging, diagnostic (SiV as a nanosized thermometer), and theranostic (nanodiamonds as drug carrier) applications.

Details

Original languageEnglish
Pages (from-to)2881-2888
Number of pages8
JournalNano letters
Volume22
Issue number7
Publication statusPublished - 15 Mar 2022
Peer-reviewedYes

External IDs

PubMed 35289621
unpaywall 10.1021/acs.nanolett.2c00040
WOS 000812727900001
Mendeley 650030b9-3d92-3129-9341-bfb0bc846d35

Keywords

Research priority areas of TU Dresden

DFG Classification of Subject Areas according to Review Boards

ASJC Scopus subject areas

Keywords

  • live cell particle tracking, Nanodiamond, near-infrared cellular imaging, silicon vacancy color center, thermometry, Diagnostic Imaging, Thermometry, Nanodiamonds/chemistry, Silicon, Drug Carriers, Silicon vacancy color center, Live cell particle tracking, Near-infrared cellular imaging

Library keywords