Severely compromised supply of patch test allergens in Europe hampers adequate diagnosis of occupational and non-occupational contact allergy. A European Society of Contact Dermatitis (ESCD), European Academy of Allergy and Clinical Immunology (EAACI), European Academy of Dermatology and Venereology (EADV) task forces ‘Contact Dermatitis’ and ‘Occupational Skin Disease’ position paper

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Swen Malte John - , University Osnabruck (Author)
  • Andreas Bonertz - , Paul-Ehrlich-Institut (Author)
  • Julia Zimmer - , Paul-Ehrlich-Institut (Author)
  • Olivier Aerts - , University of Antwerp (Author)
  • Andrea Bauer - , Department of Dermatology, University Allergy Centre, University Hospital Carl Gustav Carus Dresden (Author)
  • Maria Bova - , Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli (Author)
  • Richard Brans - , University Osnabruck (Author)
  • Stefano Del Giacco - , University Hospital of Cagliari (Author)
  • Heinrich Dickel - , Ruhr University Bochum (Author)
  • Monica Corazza - , University of Ferrara (Author)
  • Marie Noëlle Crépy - , Assistance publique – Hôpitaux de Paris (Author)
  • Rosella Gallo - , IRCCS San Martino Polyclinic Hospital (Author)
  • Jose Luis Garcia-Abujeta - , Marina Baixa Hospital (Author)
  • Ana Maria Giménez-Arnau - , Pompeu Fabra University (Author)
  • Ludger Klimek - , Center for Rhinology and Allergology Wiesbaden (Author)
  • Jean Pierre Lepoittevin - , University of Strasbourg (Author)
  • Suzana Ljubojević Hadžavdić - , University of Zagreb (Author)
  • Mihaly Matura - , Skaraborg Hospital (Author)
  • Charlotte Gotthard Mortz - , Odense University Hospital (Author)
  • Esen Özkaya - , Istanbul University (Author)
  • Maria Pesonen - , Finnish Institute of Occupational Health (Author)
  • Nadia Raison-Peyron - , CHU Montpellier (Author)
  • Thomas Rustemeyer - , Amsterdam University Medical Centers (UMC) (Author)
  • Christoph Skudlik - , University Osnabruck (Author)
  • Radoslaw Spiewak - , Jagiellonian University in Kraków (Author)
  • Luca Stingeni - , University of Perugia (Author)
  • Sari Suomela - , Finnish Institute of Occupational Health (Author)
  • Cara Symanzik - , University Osnabruck (Author)
  • James Taylor - , Case Western Reserve University (Author)
  • Maria Torres - , Hospital Regional Universitario Carlos Haya (Author)
  • Wolfgang Uter - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Ian White - , King's College London (KCL) (Author)
  • Mark Wilkinson - , Leeds Teaching Hospitals NHS Trust (Author)
  • Vera Mahler - , Paul-Ehrlich-Institut (Author)
  • Jeanne Duus Johansen - , University of Copenhagen (Author)

Abstract

Patch testing is the only clinically applicable diagnostic method for Type IV allergy. The availability of Type IV patch test (PT) allergens in Europe, however, is currently scarce. This severely compromises adequate diagnostics of contact allergy, leading to serious consequences for the affected patients. Against this background, the European Society of Contact Dermatitis (ESCD) has created a task force (TF) (i) to explore the current availability of PT substances in different member states, (ii) to highlight some of the unique characteristics of Type IV vs. other allergens and (iii) to suggest ways forward to promote and ensure availability of high-quality patch testing substances for the diagnosis of Type IV allergies throughout Europe. The suggestions of the TF on how to improve the availability of PT allergens are supported by the ESCD, the European Academy of Allergy and Clinical Immunology, and the European Academy of Dermatology and Venereology and intend to provide potential means to resolve the present medical crisis.

Details

Original languageEnglish
Pages (from-to)91-103
Number of pages13
JournalContact dermatitis
Volume91
Issue number2
Publication statusPublished - Aug 2024
Peer-reviewedYes

External IDs

PubMed 38812248
ORCID /0000-0002-4411-3088/work/169643519

Keywords

ASJC Scopus subject areas

Keywords

  • allergen provocation test, European Pharmacopoeia, marketing authorisation, patch test, regulatory framework, skin test allergens, Type IV allergy