S2k guidelines on diagnosis and treatment of linear IgA dermatosis initiated by the European Academy of Dermatology and Venereology

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Frédéric Caux - , Université Paris 13 (Author)
  • Aikaterini Patsatsi - , Aristotle University of Thessaloniki (Author)
  • Meropi Karakioulaki - , University Medical Center Freiburg (Author)
  • Emiliano Antiga - , University of Florence (Author)
  • Eulalia Baselga - , Hospital Sant Joan de Déu Barcelona (Author)
  • Luca Borradori - , University of Bern (Author)
  • Marzia Caproni - , University of Florence (Author)
  • Adela R. Cardones - , University of Kansas (Author)
  • Nisha Suyien Chandran - , National University of Singapore (Author)
  • Sören Dräger - , University of Lübeck (Author)
  • Kossara Drenovska - , Medical University Sofia (Author)
  • Matthias Goebeler - , University of Würzburg (Author)
  • Claudia Günther - , Department of Dermatology (Author)
  • Silke C. Hofmann - , Helios University Hospital Wuppertal (Author)
  • Dimitrios Ioannides - , Aristotle University of Thessaloniki (Author)
  • Pascal Joly - , CHU Hôpitaux de Rouen (Author)
  • Branka Marinović - , University of Zagreb (Author)
  • Elena Biancamaria Mariotti - , University of Florence (Author)
  • Angelo Valerio Marzano - , IRCCS Fondazione Ca'Granda – Ospedale Maggiore Policlinico - Milano, University of Milan (Author)
  • Kimberly D. Morel - , Columbia University (Author)
  • Dedee F. Murrell - , University of New South Wales (Author)
  • Catherine Prost - , Université Paris 13 (Author)
  • Miklós Sárdy - , Semmelweis University, Ludwig Maximilian University of Munich (Author)
  • Jane Setterfield - , Guy's and St Thomas' NHS Foundation Trust, King's College London (KCL) (Author)
  • Dusan Skiljevic - , University of Belgrade (Author)
  • Soner Uzun - , Akdeniz University (Author)
  • Snejina Vassileva - , Medical University Sofia (Author)
  • Giovanna Zambruno - , IRCCS Ospedale pediatrico Bambino Gesù - Roma (Author)
  • Enno Schmidt - , University of Lübeck (Author)

Abstract

Introduction: Linear IgA dermatosis (LAD) is a rare subepidermal autoimmune bullous disease (AIBD) defined by predominant or exclusive immune deposits of immunoglobulin A at the basement membrane zone of skin or mucous membranes. This disorder is a rare, clinically and immunologically heterogeneous disease occurring both in children and in adults. The aim of this project is to present the main clinical features of LAD, to propose a diagnostic algorithm and provide management guidelines based primarily on experts' opinion because of the lack of large methodologically sound clinical studies. Methods: These guidelines were initiated by the European Academy of Dermatology and Venereology (EADV) Task Force Autoimmune Bullous Diseases (AIBD). To achieve a broad consensus for these S2k consensus-based guidelines, a total of 29 experts from different countries, both European and non-European, including dermatologists, paediatric dermatologists and paediatricians were invited. All members of the guidelines committee agreed to develop consensus-based (S2k) guidelines. Prior to a first virtual consensus meeting, each of the invited authors elaborated a section of the present guidelines focusing on a selected topic, based on the relevant literature. All drafts were circulated among members of the writing group, and recommendations were discussed and voted during two hybrid consensus meetings. Results: The guidelines summarizes evidence-based and expert opinion-based recommendations (S2 level) on the diagnosis and treatment of LAD. Conclusion: These guidelines will support dermatologists to improve their knowledge on the diagnosis and management of LAD.

Details

Original languageEnglish
Pages (from-to)1006-1023
Number of pages18
JournalJournal of the European Academy of Dermatology and Venereology
Volume38
Issue number6
Publication statusPublished - Feb 2024
Peer-reviewedYes

External IDs

PubMed 38421060
ORCID /0000-0002-4330-1861/work/169643533

Keywords

Sustainable Development Goals

ASJC Scopus subject areas