Reliability of CoMFA Models:  Effects of Data Scaling and Variable Selection using a Set of Human Synovial Fluid Phospholipase A2 InhibitorsPrediction of Drug Binding Affinities by Comparative Binding Energy Analysis

Research output: Contribution to journal › Research article › Contributed › peer-review

Contributors

  • A. R. Ortiz - , European Molecular Biology Laboratory (EMBL) Heidelberg, University of Alcalá (Author)
  • M. Pastor - , University of Alcalá (Author)
  • A. Palomer - , Menarini Pharmaceuticals (Author)
  • G. Cruciani - , University of Perugia (Author)
  • F. Gago - , University of Alcalá (Author)
  • R. C. Wade - , European Molecular Biology Laboratory (EMBL) Heidelberg (Author)
  • Maria Teresa Pisabarro - , Structural Bioinformatics (Research Group), Biotechnology Center, European Molecular Biology Laboratory (EMBL) Heidelberg, University of Alcalá (Author)

Details

Original languageEnglish
Pages (from-to)4168
JournalJournal of Medicinal Chemistry
Volume40
Issue number25
Publication statusPublished - Dec 1997
Peer-reviewedYes

External IDs

doi 10.1021/jm970629l
doi 10.1021/jm9601617

Keywords