Refined validation of aortic valve pathology and pericardium replacement using polarization-sensitive OCT

Research output: Contribution to book/Conference proceedings/Anthology/ReportConference contributionContributedpeer-review

Contributors

Abstract

Polarization-sensitive optical coherence tomography (PS-OCT) was applied to calcified aortic valves as well as bovine and porcine pericardium subjected to glutaraldehyde fixation and in-vitro calcification. Retardation, optic axis orientation and depolarization images revealed collagen layers, elastin fibers and micro-calcifications in 3D. PS-OCT enables non-destructive monitoring of structural and pathological changes in valve biomaterials.

Details

Original languageEnglish
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXX
EditorsRainer A. Leitgeb, Yoshiaki Yasuno
PublisherSPIE - The international society for optics and photonics
ISBN (electronic)9781510695870
Publication statusPublished - 6 Mar 2026
Peer-reviewedYes

Publication series

SeriesProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume13837
ISSN1605-7422

Conference

TitleOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXX
Conference number30
Descriptionpart of SPIE BiOS 2026 / SPIE Photonics West 2026
Duration19 - 22 January 2026
LocationThe Moscone Center
CitySan Francisco
CountryUnited States of America

External IDs

ORCID /0000-0002-8160-3000/work/216557353
ORCID /0000-0002-8047-2774/work/216557570