Rational modification of human synovial fluid phospholipase A2 inhibitors

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • M T Pisabarro - , Structural Bioinformatics (Research Group), Biotechnology Center, European Molecular Biology Laboratory (EMBL) Heidelberg, University of Alcalá (Author)
  • A R Ortiz - , European Molecular Biology Laboratory (EMBL) Heidelberg, University of Alcalá (Author)
  • A Palomer - , Menarini Pharmaceuticals (Author)
  • F Cabré - , Menarini Pharmaceuticals (Author)
  • L García - , Menarini Pharmaceuticals (Author)
  • R C Wade - , European Molecular Biology Laboratory (EMBL) Heidelberg (Author)
  • F Gago - , University of Alcalá (Author)
  • D Mauleón - , Menarini Pharmaceuticals (Author)
  • G Carganico - , Menarini Pharmaceuticals (Author)

Details

Original languageEnglish
Pages (from-to)337-341
Number of pages5
JournalJournal of medicinal chemistry
Volume37
Issue number3
Publication statusPublished - 4 Feb 1994
Peer-reviewedYes

External IDs

Scopus 0028324779

Keywords

Keywords

  • Arthritis, Rheumatoid/drug therapy, Crystallization, Humans, Hydrogen Bonding, Models, Molecular, Molecular Structure, Phosphatidylethanolamines/chemistry, Phospholipases A/antagonists & inhibitors, Phospholipases A2, Synovial Fluid/enzymology, Thermodynamics