Radiation oncology in the era of precision medicine

Research output: Contribution to journalReview articleContributedpeer-review



Technological advances and clinical research over the past few decades have given radiation oncologists the capability to personalize treatments for accurate delivery of radiation dose based on clinical parameters and anatomical information. Eradication of gross and microscopic tumours with preservation of health-related quality of life can be achieved in many patients. Two major strategies, acting synergistically, will enable further widening of the therapeutic window of radiation oncology in the era of precision medicine: technology-driven improvement of treatment conformity, including advanced image guidance and particle therapy, and novel biological concepts for personalized treatment, including biomarker-guided prescription, combined treatment modalities and adaptation of treatment during its course.


Original languageEnglish
Pages (from-to)234-249
Number of pages16
JournalNature reviews : Cancer
Issue number4
Publication statusPublished - 24 Mar 2016

External IDs

Scopus 84962220195
PubMed 27009394
ORCID /0000-0003-4261-4214/work/147143141