Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi-walled carbon nanotubes

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Ben Newland - , Leibniz Institute of Polymer Research Dresden, Cardiff University (Author)
  • Laurent Thomas - , Leibniz Institute of Polymer Research Dresden (Author)
  • Yu Zheng - , University College Dublin (Author)
  • Martin Steinhart - , University Osnabruck (Author)
  • Carsten Werner - , Center for Regenerative Therapies Dresden, Leibniz Institute of Polymer Research Dresden (Author)
  • Wenxin Wang - , University College Dublin, Tianjin University (Author)

Abstract

Despite concerns over toxicity, carbon nanotubes have been extensively investigated for potential applications in nanomedicine because of their small size, unique properties, and ability to carry cargo such as small molecules and nucleic acids. Herein, we show that polymer nanotubes can be synthesized quickly and easily from a homopolymer of ethylene glycol dimethacrylate (EGDMA). The nanotubes formed via photo-initiated polymerization of the highly functional prepolymer, inside an anodized aluminium oxide template, have a regular structure and large internal pore and can be loaded with a fluorescent dye within minutes representing a simple alternative to multi-walled carbon nanotubes for biomedical applications.

Details

Original languageEnglish
Pages (from-to)9-18
Number of pages10
JournalJournal of interdisciplinary nanomedicine
Volume1
Issue number1
Publication statusPublished - Apr 2016
Peer-reviewedYes

External IDs

PubMedCentral PMC4959090
ORCID /0000-0003-0189-3448/work/173985717

Keywords

Research priority areas of TU Dresden

DFG Classification of Subject Areas according to Review Boards