In subjects with an infection with the novel corona virus SARS-CoV-2 and COVID-19 disease, diabetes mellitus and cardiovascular diseases are highly prevalent comorbidities. Diabetes patients with comorbidities and/or diabetes complications seem to have a higher risk for a severe course of the COVID-19 disease including the development of ARDS or multiorgan failure. The exact interrelations between diabetes and the individual clinical course of COVID-19 are not completely understood at this time. The German Diabetes Association (DDG) summarizes basic principle practice recommendations for the treatment of patients with diabetes and concomitant COVID-19 disease.