Optimal processing of Doppler signals in OCT

Research output: Contribution to book/Conference proceedings/Anthology/ReportConference contributionContributedpeer-review

Abstract

Besides structural imaging, OCT can be used to estimate axial velocities of the sample resolved in depth by Doppler processing. In Fourier domain OCT (FD-OCT), this is accomplished by measuring the phase difference (i.e. phase shift) between timely separated A-scans at the same depth. In most cases, these data are disturbed by noise caused by intrinsic noise of the OCT system, specified by the SNR, and decorrelation noise caused by the transversal movement of the optical beam relative to the sample. Since the first use of Doppler methods in OCT, many methods to reduce the phase shift noise by averaging have been presented. While all these methods use a fixed set of consecutive A-scans, the best method, exhibiting no bias and having the smallest standard deviation, was questionable. Recently, Doppler processing methods depending on the mentioned noise sources and delivering the most likely phase shift and thereby axial velocity became available. The relation of these methods to previously known methods like the Kasai estimator, maximum likelihood estimator (MLE) and joint spectral and time domain OCT (jSTdOCT) will be discussed.

Details

Original languageEnglish
Title of host publicationOptical Coherence Imaging Techniques and Imaging in Scattering Media
EditorsMaciej Wojtkowski, Brett E. Bouma
PublisherSPIE - The international society for optics and photonics, Bellingham
ISBN (electronic)9781628417067
Publication statusPublished - 2015
Peer-reviewedYes

Publication series

SeriesProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9541
ISSN1605-7422

Conference

TitleOptical Coherence Imaging Techniques and Imaging in Scattering Media
Duration21 - 23 June 2015
CityMunich
CountryGermany

External IDs

Scopus 84939628742
ORCID /0000-0003-0554-2178/work/142249859
ORCID /0009-0008-7642-8608/work/142255321
ORCID /0000-0003-2292-5533/work/142256598

Keywords

Keywords

  • Doppler processing, Flow measurement, Optical coherence tomography