We present the chemical anchoring of a DMBI-P molecule-rotor tothe Au(111) surface after a dissociation reaction. At the temperatureof 5 K, the anchored rotor shows a sequential unidirectionalrotational motion through six defined stations induced by tunneling electrons. A typical voltage pulse of 400 mV applied on aspecific location of the molecule causes a unidirectional rotationof 60° with a probability higher than 95%. When the temperatureof the substrate increases above 20 K, the anchoring is maintainedand the rotation stops being unidirectional and randomly exploresthe same six stations. Density functional theory simulationsconfirm the anchoring reaction. Experimentally, the rotationshows a clear threshold at the onset of the C–H stretch manifold,showing that the molecule is first vibrationally excited and later itdecays into the rotational degrees of freedom.