Observer based current estimation for coupled neurons

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

Abstract

The input current stimulating a neuron is not directly measurable without inference with the cell's activities. In this paper we consider two electrically coupled neurons. We present an approach to reconstruct the input current into one of the neurons using concepts from control theory. More precisely, we employ an unknown input observer to reconstruct the internal states of the neuron's model. A crucial part of this approach is the transformation of the nonlinear model into an appropriate normal form. Additional filtering yields the desired excitation current.

Details

Original languageEnglish
Pages (from-to)268-281
Number of pages14
JournalWSEAS Transactions on Systems
Volume11
Issue number7
Publication statusPublished - 2012
Peer-reviewedYes

External IDs

ORCID /0000-0002-3347-0864/work/142255188

Keywords

Keywords

  • Coupled neurons, Derivative estimation, Filter, Hodgkin-Huxley model, Observer, Relative degree