Night shift work and cardiovascular diseases among employees in Germany: five-year follow-up of the Gutenberg Health Study
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
OBJECTIVE: This study aimed to determine if there is an increased risk of incident cardiovascular diseases (CVD) resulting from cumulative night shift work in the German population-based Gutenberg Health Study (GHS).
METHODS: We examined working participants of the GHS at baseline and after five years. Cumulative night shift work in the 10 years before baseline was assessed and categorized as low (1-220 nights ≙ up to 1 year), middle (221-660 nights ≙ 1-3 years), and high (>660 nights ≙ more than 3 years) night shift exposure. Hazard ratios (HR) were estimated for incident "quality-assured CVD events" using Cox proportional hazard models.
RESULTS: At baseline, 1092 of 8167 working participants performed night shift work. During the follow-up, 202 incident cardiovascular events occurred. The crude incidence rates for CVD per 1000 person-years were 6.88 [95% confidence interval (CI) 4.80-9.55] for night shift workers and 5.19 (95% CI 4.44-6.04) for day workers. Cumulative incidence curves showed a higher cumulative incidence in workers exposed to night shift work compared to day workers after five years. The adjusted HR for incident CVD events were 1.26 (95% CI 0.68-2.33), 1.37 (95% CI 0.74-2.53) and 1.19 (95% CI 0.67-2.12) for employees in the low, middle and high night shift categories compared to employees without night shift work, respectively.
CONCLUSIONS: The observed tendencies indicate that night shift work might be negatively associated with cardiovascular health. We expect the continued follow-up will clarify the long-term impact of night shift work.
Details
Original language | English |
---|---|
Pages (from-to) | 142-151 |
Number of pages | 10 |
Journal | Scandinavian journal of work, environment & health |
Volume | 50 (2024) |
Issue number | 3 |
Early online date | 23 Jan 2024 |
Publication status | Published - 1 Apr 2024 |
Peer-reviewed | Yes |
External IDs
unpaywall | 10.5271/sjweh.4139 |
---|---|
Scopus | 85189192674 |
Keywords
Research priority areas of TU Dresden
Sustainable Development Goals
Keywords
- CVD, Gutenberg Health Study, Occupation, Rhineland-Palatinate, cardiovascular disease, cohort study, employee, incidence, longitudinal study, night shift, population-based, shift work, workplace, Cardiovascular Diseases/epidemiology, Follow-Up Studies, Humans, Prospective Studies, Risk Factors, Shift Work Schedule/adverse effects, Surveys and Questionnaires, Work Schedule Tolerance