Multi-talented MCAK: Microtubule depolymerizer with a strong grip

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

Abstract

Microtubule-depolymerizing motor proteins regulate microtubule dynamics during chromosome segregation, but whether they can independently grip the ends of shrinking kinetochore microtubules has remained unresolved. MCAK, a member of the kinesin-13 motor protein family, is now shown to grip microtubules on its own and harness the forces of microtubule disassembly.

Details

Original languageEnglish
Pages (from-to)738-740
Number of pages3
JournalNature cell biology
Volume13
Issue number7
Publication statusPublished - Jul 2011
Peer-reviewedYes

External IDs

PubMed 21725286
ORCID /0000-0002-0750-8515/work/161407041

Keywords

ASJC Scopus subject areas