Advances in flexible and self-powered sensing technologies are increasingly propelled by the integration of functional materials that couple mechanical responsiveness with electrical conversion. However, achieving high piezoelectric output in polyvinylidene fluoride (PVDF) based systems at low filler loading while maintaining long-term mechanical stability remains a critical challenge. Herein, electrospun PVDF fibrous composites containing a 2D zirconium and amide linker based metal–organic framework (MOF), DUT-211, were fabricated to enhance piezoelectric response through interfacial polarization and dipole alignment. The DUT-211/PVDF (MOPV) composite with 1 wt % MOF loading exhibits a β phase fraction of 77.1%, generating an open-circuit voltage of ∼12.4 V, a short-circuit current of ∼12.5 μA, and a peak power density of 10.5 μW cm-2 under 100 N and 5 Hz. The device retains mechanical integrity and stable output over 6000 cycles, confirming strong MOF-polymer coupling. Beyond single-point sensing, a flexible 6 × 3 pressure-sensing array demonstrates spatially resolved tactile mapping, multipoint discrimination, and programmable tactile-to-audio feedback. The synergistic combination of electrospinning-induced chain alignment and the polar 2D Zr-MOF architecture provides a route to high-signal, durable, and lightweight self-powered sensors. This study highlights the potential of amide-based MOFs in tailoring PVDF for efficient mechanical-to-electrical signal conversion and provides a scalable design pathway for next-generation self-powered sensing platforms, interactive electronics, and intelligent wearable technologies.