Method for Expanding Monocytes
Research output: Intellectual property › Patent application/Patent
Contributors
Abstract
The invention relates to an ex vivo method for expanding monocytes, macrophages or dendritic cells, which method comprises inhibiting the expression or the activity of MafB and c-Maf in monocytes, macrophages or dendritic cells; and expanding the cells in the presence of at least one cytokine or an agonist of cytokine receptor signalling.
Details
The invention relates to an ex vivo method for expanding monocytes, macrophages or dendritic cells, which method comprises inhibiting the expression or the activity of MafB and c-Maf in monocytes, macrophages or dendritic cells; and expanding the cells in the presence of at least one cytokine or an agonist of cytokine receptor signalling.
| Original language | English |
|---|---|
| IPC (International Patent Classification) | A61K 35/ 12 A N |
| Patent number | US2014127268 |
| Country/Territory | Germany |
| Priority date | 5 Nov 2013 |
| Priority number | US201314072494 |
| Publication status | Published - 8 May 2014 |
| Externally published | Yes |
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