Cellular Automata (CA) is a nature-inspired and widespread computational model which is based on the collective and emergent parallel computing capability of units (cells) locally interconnected in an abstract brain-like structure. Each such unit, referred as CA cell, performs simplistic computations/processes. However, a network of such identical cells can exhibit nonlinear behavior and be used to model highly complex physical phenomena and processes and to solve problems that are highly complicated for conventional computers. Brain activity has always been considered one of the most complex physical processes and its modeling is of utter importance. This work combines the CA parallel computing capability with the nonlinear dynamics of the memristor, aiming to model brain activity during the epileptic seizures caused by the spreading of pathological dynamics from focal to healthy brain regions. A CA-based confrontation extended to include long-range interactions, combined with the recent notion of memristive electronics, is thus proposed as a modern and promising parallel approach to modeling of such complex physical phenomena. Simulation results show the efficiency of the proposed design and the appropriate reproduction of the spreading of an epileptic seizure.