Meeting in the Middle: Towards Successful Multidisciplinary Bioimage Analysis Collaboration

Research output: Contribution to journalResearch articleContributedpeer-review


  • Anjalie Schlaeppi - , Morgridge Institute for Research (Author)
  • Wilson Adams - , Vanderbilt University (Author)
  • Robert Haase - , Clusters of Excellence PoL: Physics of Life (Author)
  • Jan Huisken - , Morgridge Institute for Research (Author)
  • Ryan B MacDonald - , University College London (Author)
  • Kevin W Eliceiri - , Morgridge Institute for Research (Author)
  • Elisabeth C Kugler - , Clusters of Excellence PoL: Physics of Life, University College London (Author)


With an increase in subject knowledge expertise required to solve specific biological questions, experts from different fields need to collaborate to address increasingly complex issues. To successfully collaborate, everyone involved in the collaboration must take steps to "meet in the middle". We thus present a guide on truly cross-disciplinary work using bioimage analysis as a showcase, where it is required that the expertise of biologists, microscopists, data analysts, clinicians, engineers, and physicists meet. We discuss considerations and best practices from the perspective of both users and technology developers, while offering suggestions for working together productively and how this can be supported by institutes and funders. Although this guide uses bioimage analysis as an example, the guiding principles of these perspectives are widely applicable to other cross-disciplinary work.


Original languageEnglish
JournalFrontiers in bioinformatics
Publication statusPublished - Apr 2022

External IDs

PubMedCentral PMC9122012
Scopus 85161355721