Mechanobiology: Correlation between mechanical stability of microcapsules studied by afm and impact of cell-induced stresses

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Mihaela Delcea - , Max Planck Institute of Colloids and Interfaces (Author)
  • Stephan Schmidt - , Max Planck Institute of Colloids and Interfaces (Author)
  • Raghavendra Palankar - , Max Planck Institute for Biophysical Chemistry (Karl Friedrich Bonhoeffer Institute) (Author)
  • Paulo A.L. Fernandes - , Max Planck Institute of Colloids and Interfaces (Author)
  • Andreas Fery - , University of Bayreuth (Author)
  • Helmuth Möhwald - , Max Planck Institute of Colloids and Interfaces (Author)
  • André G. Skirtach - , Max Planck Institute of Colloids and Interfaces (Author)

Abstract

In a novel approach to the study of cell mechanics, a colloidal probe AFM is combined with a fluorescence microscope to investigate the mechanical properties and release from polymeric microcapsules and to correlate these data with release upon intracellular incorporation and cell-induced stresses.

Details

Original languageEnglish
Pages (from-to)2858-2862
Number of pages5
JournalSmall
Volume6
Issue number24
Publication statusPublished - 20 Dec 2010
Peer-reviewedYes
Externally publishedYes

External IDs

PubMed 21086520

Keywords

Keywords

  • atomic force microscopy, cell mechanics, intracellular incorporation, mechanobiology, polymeric microcapsules