Male meiosis: Y keep it silenced?
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
What drives defective spermatocytes into apoptosis during mid-pachytene? A recent study identifies the first mid-pachytene 'killer' genes: two Y-linked transcription factors, the Zfy1/2 gene pair, must be silenced to avoid apoptosis.
Details
Original language | English |
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Pages (from-to) | R1022-4 |
Journal | Current Biology |
Volume | 20 |
Issue number | 23 |
Publication status | Published - 7 Dec 2010 |
Peer-reviewed | Yes |
External IDs
Scopus | 78650128268 |
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PubMed | 21145018 |
Keywords
Keywords
- Animals, Apoptosis/genetics, Female, Gene Silencing, Humans, Male, Meiosis, Spermatocytes/physiology, Transcription Factors/genetics, Y Chromosome