Male meiosis: Y keep it silenced?
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
What drives defective spermatocytes into apoptosis during mid-pachytene? A recent study identifies the first mid-pachytene 'killer' genes: two Y-linked transcription factors, the Zfy1/2 gene pair, must be silenced to avoid apoptosis.
Details
| Original language | English |
|---|---|
| Pages (from-to) | R1022-4 |
| Journal | Current Biology |
| Volume | 20 |
| Issue number | 23 |
| Publication status | Published - 7 Dec 2010 |
| Peer-reviewed | Yes |
External IDs
| Scopus | 78650128268 |
|---|---|
| PubMed | 21145018 |
Keywords
Keywords
- Animals, Apoptosis/genetics, Female, Gene Silencing, Humans, Male, Meiosis, Spermatocytes/physiology, Transcription Factors/genetics, Y Chromosome