The exploitation of data as well as hardware properties is a core aspect for efficient data management. This holds in particular for the field of in-memory data processing. Aside from increasing main memory capacities, in-memory data processing also benefits from novel processing concepts based on lightweight compressed data. To speed up compression as well as decompression, an active research field deals with the specialization of these algorithms to hardware features such as vectorization using SIMD instructions. Most of the vectorized implementations have been proposed for 128 bit vector registers. However, hardware vendors still increase the vector register sizes, whereby a straightforward transformation to these wider vector sizes is possible in most-cases. Thus, we systematically investigated the impact of different SIMD instruction set extensions with wider vector sizes on the behavior of straightforward transformed implementations. In this paper, we will describe our evaluation methodology and present selective results of our exhaustive evaluation. In particular, we will highlight some challenges and present first approaches to tackle them.