Light therapy for bipolar disorders: Clinical recommendations from the international society for bipolar disorders (ISBD) Chronobiology and Chronotherapy Task Force

Research output: Contribution to journal › Review article › Contributed › peer-review

Contributors

  • Pierre A. Geoffroy - , Public Assistance - Paris Hospitals, Université Paris Cité, GHU Paris Psychiatrie & Neuro sciences, University of Strasbourg (Author)
  • Laura Palagini - , University of Pisa (Author)
  • Tone E.G. Henriksen - , Fonna Health Trust (Author)
  • Patrice Bourgin - , University of Strasbourg, University Hospital of Strasbourg (Author)
  • Corrado Garbazza - , University of Basel (Author)
  • Claude Gronfier - , Lyon Neuroscience Research Center (CRNL) (Author)
  • Yuichi Esaki - , Fujita Health University (Author)
  • Diego C. Fernandez - , University of Cincinnati (Author)
  • Raymond W. Lam - , University of British Columbia (Author)
  • Heon Jeong Lee - , Korea University (Author)
  • Michel Lejoyeux - , Public Assistance - Paris Hospitals, Université Paris Cité, GHU Paris Psychiatrie & Neuro sciences (Author)
  • Julia Maruani - , Public Assistance - Paris Hospitals, Université Paris Cité, GHU Paris Psychiatrie & Neuro sciences (Author)
  • Klaus Martiny - , University of Copenhagen (Author)
  • Greg Murray - , Swinburne University of Technology (Author)
  • Rixt F. Riemersma-Van Der Lek - , GGZ Drenthe Mental Health Institution (Author)
  • Philipp Ritter - , Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus Dresden (Author)
  • Peter F.J. Schulte - , Mental Health Services Noord-Holland-Noord (Author)
  • Daniel J. Smith - , University of Edinburgh (Author)
  • Michael Terman - , Center For Environmental Therapeutics, Columbia University (Author)
  • Jamie M. Zeitzer - , Stanford University (Author)
  • Dorothy K. Sit - , Northwestern University (Author)

Abstract

The International Society for Bipolar Disorders (ISBD) Chronobiology and Chronotherapy Task Force conducted a comprehensive review to deliver concise evidence-based recommendations on the use of bright light therapy (BLT) for bipolar disorder (BD). Adjunctive BLT is likely an efficacious acute treatment for bipolar depression as implicated by higher quality evidence. The position of maintenance BLT for relapse prevention awaits further investigation. Protocols of effective BLT in BD are similar to parameters indicated for treatment of seasonal and non-seasonal major depressive disorder. Anti-manic prophylaxis (especially for BD-I) and clinical monitoring are recommended with initiation of and ongoing light treatment. Administer BLT daily, preferably in the morning or at mid-day. If mornings are prohibitive, then mid-day exposure, implemented to avoid excessively early wake times, is an acceptable alternative. Informed by the literature, target 30 min/day of BLT exposure. Patients wary of emergent hypomania or partial responders, can initiate 15 min/day and increase by 15 min each week to full response (or 30–60 min/day by the fourth week). Consider patient centred outcome assessments to evaluate mood response, safety and side effects. Clinical improvement is typically observed within 1–2 weeks, with response/remission expected by 4–6 weeks. Integration of BLT with other chronotherapeutic strategies may enhance long-term efficacy.

Details

Original languageEnglish
Pages (from-to)249-264
Number of pages16
JournalDialogues in Clinical Neuroscience
Volume27
Issue number1
Publication statusPublished - 2025
Peer-reviewedYes

External IDs

PubMed 40705857

Keywords

Sustainable Development Goals

Keywords

  • Bipolar disorder, chronotherapy, depression, light therapy, phototherapy, seasonal affective disorder