Cycloisomerizations are powerful skeletal rearrangements that allow the construction of complex molecular architectures in an atom-economic way. We present here an unusual type of cyclopropyl enyne cycloisomerization that couples the process of a cycloisomerization with the activation of a C−C bond in cyclopropanes. A set of substituted non-canonical tricyclic cyclobutanes were synthesized under mild conditions using [(Ph3P)2Fe(CO)(NO)]BF4 as catalyst in good to excellent yields with high levels of stereocontrol.
|Journal||Angewandte Chemie - International Edition|
|Early online date||12 Jul 2022|
|Publication status||Published - 19 Sep 2022|
Research priority areas of TU Dresden
DFG Classification of Subject Areas according to Review Boards
Subject groups, research areas, subject areas according to Destatis
- Cyclobutanes, Cycloisomerization, Cyclopropanes, Iron Catalysis, Rearrangement, Iron, Catalysis, Cyclobutanes/chemistry, Cyclopropanes/chemistry