Investigation of the microscopic and molecular processes underlying the corneal cross-linking therapy

Jan Rix; Svea Steuer; Jonas Golde; Fadi Husein; Felix Lochmann; Steven Melcher; Gerald Steiner; Julia Walther; Frederik Raiskup; Ramin Khoramnia; Robert Herber

doi:10.1117/12.3097970

Investigation of the microscopic and molecular processes underlying the corneal cross-linking therapy

Research output: Contribution to book/Conference proceedings/Anthology/Report › Conference contribution › Contributed › peer-review

Contributors

Jan Rix - , Department of Medical Physics and Biomedical Engineering (Author)
Svea Steuer - , Department of Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring (Author)
Jonas Golde - , Department of Medical Physics and Biomedical Engineering, Department of Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring, Fraunhofer Institute for Material and Beam Technology (Author)
Fadi Husein - , Department of Ophthalmology (Author)
Felix Lochmann - , Department of Ophthalmology (Author)
Steven Melcher - , Department of Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring (Author)
Gerald Steiner - , Department of Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring (Author)
Julia Walther - , Department of Medical Physics and Biomedical Engineering (Author)
Frederik Raiskup - , Department of Ophthalmology (Author)
Ramin Khoramnia - , Department of Ophthalmology (Author)
Robert Herber - , Department of Ophthalmology (Author)

Abstract

Investigations on porcine eyes by Brillouin-Raman spectroscopy and polarization-sensitive optical coherence tomography revealed that mechanical stiffening of corneal cross-linking therapy is based on fiber alignment and hydration, but not on changes in the molecular structure.

Details

Original language	English
Title of host publication	Optical Systems for Mechanical and Biophysical Investigation
Editors	Brendan F. Kennedy, Giuliano Scarcelli
Publisher	SPIE - The international society for optics and photonics
ISBN (electronic)	9781510698093
Publication status	Published - 18 Dec 2025
Peer-reviewed	Yes

Publication series

Series	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	13936
ISSN	1605-7422

Conference

Title	Optical Systems for Mechanical and Biophysical Investigation 2025
Abbreviated title	OMBI 2025
Duration	22 - 26 June 2025
Website	https://www.optica.org/events/meeting_archives/2025/european_conferences_on_biomedical_optics/
City	München
Country	Germany

External IDs

ORCID	/0000-0003-2292-5533/work/203071601
ORCID	/0000-0002-8160-3000/work/203071725
ORCID	/0009-0002-1419-8698/work/203072025
ORCID	/0000-0001-5283-0290/work/203072286
ORCID	/0000-0003-0829-7577/work/203072364
ORCID	/0000-0002-7625-343X/work/203072384

Research Portal of the TU Dresden

Investigation of the microscopic and molecular processes underlying the corneal cross-linking therapy

Contributors

Abstract

Details

Publication series

Conference

External IDs

Keywords

ASJC Scopus subject areas