Intrapulmonary and cutaneous siliconomas after silent silicone breast implant failure

Research output: Contribution to journalResearch articleContributedpeer-review


  • Adrian Dragu - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Dirk Theegarten - , University of Duisburg-Essen (Author)
  • Alexander D. Bach - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Elias Polykandriotis - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Andreas Arkudas - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Ulrich Kneser - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Raymund E. Horch - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Giulio Ingianni - , Helios Hospital Group (Author)


Since the implementation and use of silicone implants in breast surgery the risks are published and discussed. Especially, the incidence of late silicone implant rupture and its potential risk to induce local siliconomas are still under discussion and not sufficiently evaluated. So far literature data offer no information of intrapulmonal or peripheral located cutaneous siliconomas because of systemic migration of silicone after breast augmentation. In light of silicones checkered history, and given the large and growing number of women who choose to undergo breast augmentation surgery each year, the presented clinical findings in our study are likely to be of interest to medical professionals, producers, and consumers alike. We present six female patients with an average age of 55 (±5) years with bilateral rupture of silicone implants after breast augmentation for aesthetic reasons. The average time after operation was 18 (±6) years. In five patients, we identified peripheral located cutaneous siliconomas and one patient suffered from an intrapulmonal siliconoma. The diagnosis of bilateral rupture of the silicone implants was performed preoperatively by MRI-scans. All five peripheral cutaneous siliconomas and the intrapulmonal siliconoma were validated by histopathologic analysis. Six female patients suffered from bilateral rupture of silicone implants after breast augmentation. In five patients, we identified peripheral located cutaneous siliconomas which were surgically excised. One patient suffered from an intrapulmonal siliconoma. In this unique case a lobectomy with resection of the pulmonal segment 10 had to be performed. Clinical findings of peripheral cutaneous and even intrapulmonary siliconomas after bilateral rupture of silicone breast implants indicate a systemic hematogen or lymphatic pathway of silicone. These findings suggest that it is mandatory to inform the patient about the potential risk of local siliconomas, but also about the potential risk of peripheral cutaneous or even intrapulmonary siliconomas caused by systemic hematogen or lymphatic pathways of silicone after silent implant failure.


Original languageEnglish
Pages (from-to)496-499
Number of pages4
JournalBreast Journal
Issue number5
Publication statusPublished - Sept 2009
Externally publishedYes

External IDs

PubMed 19624416
ORCID /0000-0003-4633-2695/work/145698758


ASJC Scopus subject areas


  • Breast augmentation, Intrapulmonary siliconoma, Silent breast implant failure, Silicone