Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

Abstract

Pre-treatment of mice with β-glucan, an agonist of trained immunity responses, leads to epigenetic changes in granulopoiesis and neutrophil function to drive anti-tumor immune responses.

Details

Original languageEnglish
Pages (from-to)771-785.e12
JournalCell
Volume183
Issue number3
Publication statusPublished - 29 Oct 2020
Peer-reviewedYes

External IDs

PubMed 33125892
ORCID /0000-0002-3274-7163/work/142249703

Keywords

Sustainable Development Goals

Keywords

  • cancer immunotherapy, granulopoiesis, inflammation, innate immune memory, interferon, neutrophils, trained immunity, β-glucan

Library keywords