Incidence of type 2 diabetes and metabolic syndrome by Occupation - 10-Year follow-up of the Gutenberg Health Study

Research output: Contribution to journal › Research article › Contributed › peer-review

Contributors

  • Juliane Bauer - , Federal Institute for Occupational Safety and Health (Author)
  • Janice Hegewald - , Federal Institute for Occupational Safety and Health (Author)
  • Karin Rossnagel - , Federal Institute for Occupational Safety and Health (Author)
  • Sylvia Jankowiak - , Federal Institute for Occupational Safety and Health (Author)
  • Michaela Prigge - , Federal Institute for Occupational Safety and Health (Author)
  • Julian Chalabi - , University Medical Center Mainz (Author)
  • Matthias Nübling - , University of Freiburg (Author)
  • Alice Freiberg - , Institute and Policlinic of Occupational and Social Medicine (Author)
  • Merle Riechmann-Wolf - , University Medical Center Mainz (Author)
  • Pavel Dietz - , University Medical Center Mainz (Author)
  • Philipp S Wild - , Institute of Molecular Biology (IMB) gGmbH (Author)
  • Thomas Koeck - , University Medical Center Mainz (Author)
  • Manfred E Beutel - , University Medical Center Mainz (Author)
  • Norbert Pfeiffer - , University Medical Center Mainz (Author)
  • Karl J Lackner - , University Medical Center Mainz (Author)
  • Thomas Münzel - , University Medical Center Mainz (Author)
  • Konstantin Strauch - , University Medical Center Mainz (Author)
  • Philipp Lurz - , University Medical Center Mainz (Author)
  • Oliver Tüscher - , University Medical Center Mainz (Author)
  • Julia Weinmann-Menke - , University Medical Center Mainz (Author)
  • Stavros Konstantinides - , University Medical Center Mainz (Author)
  • Andreas Seidler - , Institute and Policlinic of Occupational and Social Medicine (Author)

Abstract

BACKGROUND: In view of demographic change, rising retirement age, and a growing shortage of skilled workers, it is increasingly important to prevent widespread diseases such as type 2 diabetes or its risk factor metabolic syndrome. Since the workplace is an important setting for preventive measures and little is known about incident cases in the working population, the aim of this study was to identify vulnerable occupational groups for whom these interventions are particularly appropriate. Therefore, we investigated the 10-year incidence of type 2 diabetes and metabolic syndrome across occupational groups in Germany.

METHODS: Employees of the population-based Gutenberg-Health-Study (GHS) were examined at baseline (2007-2012) and 10 years later. We calculated age- and sex-standardised incidence rates and standardised incidence ratios (SIR) with a 95% confidence interval (CI) for occupations, job complexity levels, and supervisory and managerial positions. 5954 persons at risk for type 2 diabetes and 5103 at risk for metabolic syndrome were observed.

RESULTS: Between baseline and follow-up, 388 cases of type 2 diabetes and 1104 cases of metabolic syndrome occurred, and standardised incidences were 6.9% and 22.6%, respectively. The highest incidence of type 2 diabetes was observed in the occupational group "food production and processing" (20.7%) with a threefold increased incidence (SIR = 3.0, 95% CI 1.8-4.7) compared to the total working population of the GHS. Employees in "metal production, processing and construction" had the highest incidence of metabolic syndrome and a two times higher SIR (48.5%; SIR = 2.1, 95% CI 1.4-2.9). There was also a high incidence of both type 2 diabetes and metabolic syndrome in "cleaners" (16.5% and 34.8%) and "drivers and mobile plant operators" (14.8% and 41.2%). An increased incidence of type 2 diabetes and metabolic syndrome was observed with decreasing job complexity levels.

CONCLUSIONS: This study shows wide differences in the incidence of type 2 diabetes and metabolic syndrome between occupational groups and highlights the vulnerability of certain occupations. As the workplace is an important platform for interventions, the findings of this study could guide the development of more nuanced and effective workplace health initiatives to promote a healthier workforce for the future.

Details

Original languageEnglish
Article number502
Number of pages15
JournalBMC Public Health
Volume25 (2025)
Issue number1
Publication statusPublished - 7 Feb 2025
Peer-reviewedYes

External IDs

PubMedCentral PMC11803924
ORCID /0000-0001-7668-4734/work/178384571
unpaywall 10.1186/s12889-025-21732-5
Scopus 85218259622

Keywords

Sustainable Development Goals

  • SDG 2 - Zero Hunger - Adult, Aged, Diabetes Mellitus, Type 2/epidemiology, Female, Follow-Up Studies, Germany/epidemiology, Humans, Incidence, Male, Metabolic Syndrome/epidemiology, Middle Aged, Occupations/statistics & numerical data, Risk Factors, Cardiometabolic, Epidemiology, Incidence, Longitudinal, Metabolic syndrome, Occupation, Prevalence, Type 2 diabetes, population-based
  • SDG 3 - Good Health and Well-being - Adult, Aged, Diabetes Mellitus, Type 2/epidemiology, Female, Follow-Up Studies, Germany/epidemiology, Humans, Incidence, Male, Metabolic Syndrome/epidemiology, Middle Aged, Occupations/statistics & numerical data, Risk Factors, Cardiometabolic, Epidemiology, Incidence, Longitudinal, Metabolic syndrome, Occupation, Prevalence, Type 2 diabetes, population-based

Keywords

  • Adult, Aged, Diabetes Mellitus, Type 2/epidemiology, Female, Follow-Up Studies, Germany/epidemiology, Humans, Incidence, Male, Metabolic Syndrome/epidemiology, Middle Aged, Occupations/statistics & numerical data, Risk Factors, Cardiometabolic, Epidemiology, Incidence, Longitudinal, Metabolic syndrome, Occupation, Prevalence, Type 2 diabetes, population-based