Impedance-based infection model of human neutrophils

Research output: Contribution to book/conference proceedings/anthology/reportChapter in book/anthology/reportContributed

Contributors

Abstract

Neutrophil granulocytes play an important role in the human immune defence. One of their weapons against bacteria and fungi is the release of Neutrophil Extracellular Traps (NETs) which form in great amounts a biofilm. Electrical Impedance Spectroscopy (EIS) enables the examination of the NET-formation to determine the reaction parameters and to investigate the state of wound inflammation. In this work we analyze the behaviour of neutrophils in vitro and develop an empiric model of the states of NET-formation. This model can be used to develop a wound sensor which monitors the NET-formation caused by an infection in vivo.

Details

Original languageEnglish
Title of host publicationLecture Notes on Impedance Spectroscopy
EditorsOlfa Kanoun
Place of PublicationLondon
PublisherRoutledge, London
Pages59-63
Number of pages5
VolumeVol. 4
ISBN (print)9781138001404
Publication statusPublished - 18 Nov 2013
Peer-reviewedNo

External IDs

researchoutputwizard legacy.publication#57092
Scopus 85054621114