Image quality enhancement for ultra-thin lensless multi-core fiber phase endoscopes

Research output: Contribution to book/Conference proceedings/Anthology/ReportConference contributionContributedpeer-review

Abstract

Quantitative phase imaging (QPI) is an emerging label-free biomedical imaging modality. However, achieving high-fidelity QPI through an optical multicore fiber remains challenging. We demonstrate a novel phase reconstruction algorithm tailored for QPI through a lensless multi-core fiber (MCF) with a diameter of less than half a millimeter. Furthermore, precise reconstruction of the complex light field enables digital refocusing, providing flexible working distance for the lensless endoscope. Moreover, a total variation model is implemented to reduce the noise in the reconstructed images, enhancing the endoscopic image quality. This powerful ultra-thin QPI probe could open new perspectives for endoscopic imaging.

Details

Original languageEnglish
Title of host publicationQuantitative Phase Imaging IX
EditorsYang Liu, YongKeun Park
PublisherSPIE - The international society for optics and photonics, Bellingham
ISBN (electronic)9781510658837
Publication statusPublished - 2023
Peer-reviewedYes

Publication series

SeriesProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume12389
ISSN1605-7422

Conference

TitleQuantitative Phase Imaging IX 2023
Duration28 - 30 January 2023
CitySan Francisco
CountryUnited States of America

Keywords

Keywords

  • Biophotonics, Endoscopy, Microscopy, Multi-core fiber, Phase retrieval, Quantitative phase imaging