ICTV Virus Taxonomy Profile: Retroviridae 2021

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • John Coffin - , Tufts University (Author)
  • Jonas Blomberg - , Uppsala University (Author)
  • Hung Fan - , Dominican University of California (Author)
  • Robert Gifford - , Center for Virus Research (Author)
  • Theodora Hatziioannou - , Rockefeller University (Author)
  • Dirk Lindemann - , Institute of Medical Microbiology and Virology (Author)
  • Jens Mayer - , University Hospital of Saarland (Author)
  • Jonathan Stoye - , The Francis Crick Institute (Author)
  • Michael Tristem - , Imperial College London (Author)
  • Welkin Johnson - , Boston College (Author)
  • Ictv Report Consortium - (Author)

Abstract

Viruses in the family Retroviridae are found in a wide variety of vertebrate hosts. Enveloped virions are 80-100 nm in diameter with an inner core containing the viral genome and replicative enzymes. Core morphology is often characteristic for viruses within the same genus. Replication involves reverse transcription and integration into host cell DNA, resulting in a provirus. Integration into germline cells can result in a heritable provirus known as an endogenous retrovirus. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Retroviridae, which is available at ictv.global/report/retroviridae.

Details

Original languageEnglish
JournalJournal of General Virology
Volume102
Issue number12
Publication statusPublished - Dec 2021
Peer-reviewedYes

External IDs

PubMedCentral PMC8744268
Scopus 85122904902
ORCID /0000-0002-0320-4223/work/150884954

Keywords

Keywords

  • Animals, DNA Viruses/classification, Genome, Viral, Host Specificity, Retroviridae/classification, Vertebrates/virology, Virion/ultrastructure, Virus Replication