HIV-Erstdiagnosen in Deutschland im Jahr 2014 – eine regionale Analyse

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • HIV-Regional Studiengruppe - (Author)
  • Department of Dermatology
  • Jena University Hospital
  • St. Joseph Hospital Berlin Tempelhof
  • Asklepios Klinik St. Georg
  • Uniklinik Köln
  • Klinikum Rechts der Isar (MRI TUM)
  • Charité – Universitätsmedizin Berlin
  • Infektiologikum Frankfurt, Frankfurt, Deutschland.
  • Ambulanzzentrum des UKE GmbH, Bereich Infektiologie, Hamburg, Deutschland.
  • Hospital of the Ludwig-Maximilians-University (LMU) Munich
  • University Hospital Frankfurt

Abstract

BACKGROUND: Information on testing units in health care is scarce, particularly the group of late-presenters among the HIV-first diagnoses is still a challenge in Germany.

AIM: Analysis of the impact of testing units on and reasons for the prevalence of HIV-first diagnoses and late presentation, taking 2014 for illustrative purposes.

MATERIAL AND METHODS: Cross-sectional analysis of all individuals, treated in the Network HIV-Regional who were first diagnosed with HIV in 2014; patient characteristics, demographic and clinical data, including information on HIV testing were collected retrospectively and in a decentralised manner, pseudonymized and statistically evaluated.

RESULTS: A total of 971 individuals with HIV-first diagnosis from 31 specialised care centres throughout Germany (15 hospitals, 16 private practices) represented 27.5% of all National HIV-first diagnoses -registrations from Robert Koch Institute for 2014, with similar results for CD4-cell count and HIV-transmission risk. The most common test site was a hospital (34.8%), followed by the office of a family doctor (19.6%) and medical specialist (16.1%). If the first diagnosis was established in hospital, then the patients were on average older than those tested on an ambulant care basis (42 vs. 37 years, p=0.001); moreover, the HI-viral load was higher (585 vs. 270 thousand copies/mL, p<0.001) and the CD4-cell count lower (265 vs. 414/µL, p<0.001). In 208/971 individuals with first diagnosis, at least one AIDS-defining disease was found, most frequently pneumocystis-pneumonia (43.8%), candidiasis (36.5%) and Kaposi sarcoma (10.6%). A regional comparison revealed that in eastern Germany, for first diagnosed HIV-patients were younger, had a higher HIV-RNA viral load and also more often clinical AIDS.

CONCLUSION: This analysis of HIV-Regional for 2014 enables a deeper insight into HIV first diagnoses, on the eve of the introduction of important prevention tools in Germany, e. g., HIV home testing and pre-exposure prophylaxis. This cross-sectional analysis was representative for Germany and underscores the importance of specialised hospitals, in particular for eastern Germany, and furthermore the involvement of late-presenters into HIV health care.

Translated title of the contribution
HIV First Diagnoses in Germany in 2014 - A Regional Analysis

Details

Original languageGerman
Pages (from-to)e45-e52
Journal Das Gesundheitswesen : Sozialmedizin, Gesundheits-System-Forschung, medizinischer Dienst, public health, öffentlicher Gesundheitsdienst, Versorgungsforschung
Volume84
Issue number11
Early online date17 Feb 2022
Publication statusPublished - Nov 2022
Peer-reviewedYes

External IDs

Scopus 85125520608

Keywords

Sustainable Development Goals

Keywords

  • Acquired Immunodeficiency Syndrome, Cross-Sectional Studies, Germany/epidemiology, HIV Infections/diagnosis, Humans, Retrospective Studies, CD4, HIV, AIDS, Late presentation

Library keywords