High-Dose Glucocorticoids for the Treatment of Sudden Hearing Loss
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
- Martin Luther University Hospital
- Robert Bosch Krankenhaus Stuttgart
- University of Tübingen
- Martin Luther University Halle-Wittenberg
- Scientific Institute for Applied Oto-Rhino-Laryngology of the German Professional Association of ENT Surgeons
- AZ Sint-Jan Brugge
- University Hospital Gießen and Marburg
- Rostock University Medical Centre
- ENT Practice
- Hospital Sankt Georg Leipzig gGmbH
- University Hospital
- SRH Wald-Klinikum Gera
- Ruhr University Bochum
- Jena University Hospital
- Friedrich-Alexander University Erlangen-Nürnberg
- University of Regensburg
- Heinrich-Braun-Klinikum gGmbH
- SRH Zentralklinikum Suhl
Abstract
High-Dose Glucocorticoids for Sudden Hearing LossThis trial compared courses of high-dose intravenous prednisolone or high-dose oral dexamethasone versus standard-dose oral prednisone in adults with idiopathic sudden sensorineural hearing loss. At 30 days, systemic high-dose glucocorticoid therapy was not superior to a lower-dose regimen with respect to change in hearing threshold, and it was associated with a higher risk of side effects.
Details
| Original language | English |
|---|---|
| Pages (from-to) | EVIDoa2300172 |
| Journal | NEJM evidence |
| Volume | 3 |
| Issue number | 1 |
| Publication status | Published - Jan 2024 |
| Peer-reviewed | Yes |
Keywords
Keywords
- Adult, Humans, Glucocorticoids, Hearing Loss, Sudden/chemically induced, Treatment Outcome, Dexamethasone, Prednisone