Growth across scales: Dynamic signaling impacts tissue size and shape

Research output: Contribution to journalReview articleContributedpeer-review

Contributors

Abstract

Organ and tissue growth result from an integration of biophysical communication across biological scales, both in time and space. In this review, we highlight new insight into the dynamic connections between control mechanisms operating at different length scales. First, we consider how the dynamics of chemical and electrical signaling in the shape of gradients or waves affect spatiotemporal signal interpretation. Then, we discuss the mechanics underlying dynamic cell behavior during oriented tissue growth, followed by the connections between signaling at the tissue and organismal levels.

Details

Original languageEnglish
Pages (from-to)50-57
Number of pages8
JournalCurrent opinion in cell biology
Volume73
Publication statusPublished - Dec 2021
Peer-reviewedYes

External IDs

ORCID /0000-0002-6023-3880/work/153110500
Scopus 85108611789

Keywords

Keywords

  • Models, Biological, Morphogenesis, Signal Transduction