Graphene Biodevices for Early Disease Diagnosis Based on Biomarker Detection
Research output: Contribution to journal › Review article › Contributed › peer-review
Contributors
Abstract
The early diagnosis of diseases plays a vital role in healthcare and the extension of human life. Graphene-based biosensors have boosted the early diagnosis of diseases by detecting and monitoring related biomarkers, providing a better understanding of various physiological and pathological processes. They have generated tremendous interest, made significant advances, and offered promising application prospects. In this paper, we discuss the background of graphene and biosensors, including the properties and functionalization of graphene and biosensors. Second, the significant technologies adopted by biosensors are discussed, such as field-effect transistors and electrochemical and optical methods. Subsequently, we highlight biosensors for detecting various biomarkers, including ions, small molecules, macromolecules, viruses, bacteria, and living human cells. Finally, the opportunities and challenges of graphene-based biosensors and related broad research interests are discussed.
Details
Original language | English |
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Pages (from-to) | 3841-3881 |
Number of pages | 41 |
Journal | ACS sensors |
Volume | 6 |
Issue number | 11 |
Publication status | Published - 26 Nov 2021 |
Peer-reviewed | Yes |
External IDs
PubMed | 34696585 |
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ORCID | /0000-0002-9899-1409/work/142249205 |
Keywords
Research priority areas of TU Dresden
Sustainable Development Goals
ASJC Scopus subject areas
Keywords
- biodevices, biomarker detection, circulating tumor cells, early diagnosis, electrochemical biosensors, field-effect transistors, functionalization, graphene, microfluidic system, optical biosensors