Graphene Biodevices for Early Disease Diagnosis Based on Biomarker Detection

Research output: Contribution to journalReview articleContributedpeer-review

Contributors

Abstract

The early diagnosis of diseases plays a vital role in healthcare and the extension of human life. Graphene-based biosensors have boosted the early diagnosis of diseases by detecting and monitoring related biomarkers, providing a better understanding of various physiological and pathological processes. They have generated tremendous interest, made significant advances, and offered promising application prospects. In this paper, we discuss the background of graphene and biosensors, including the properties and functionalization of graphene and biosensors. Second, the significant technologies adopted by biosensors are discussed, such as field-effect transistors and electrochemical and optical methods. Subsequently, we highlight biosensors for detecting various biomarkers, including ions, small molecules, macromolecules, viruses, bacteria, and living human cells. Finally, the opportunities and challenges of graphene-based biosensors and related broad research interests are discussed.

Details

Original languageEnglish
Pages (from-to)3841-3881
Number of pages41
JournalACS sensors
Volume6
Issue number11
Publication statusPublished - 26 Nov 2021
Peer-reviewedYes

External IDs

PubMed 34696585
ORCID /0000-0002-9899-1409/work/142249205

Keywords

Sustainable Development Goals

Keywords

  • biodevices, biomarker detection, circulating tumor cells, early diagnosis, electrochemical biosensors, field-effect transistors, functionalization, graphene, microfluidic system, optical biosensors

Library keywords