Giving birth gives birth to neurons: In mice, pregnancy results in new neurons that support recognition of pups

Research output: Contribution to journalResearch articleContributedpeer-review

Abstract

Neurogenesis (the birth of new neurons from stem cells) is very limited in the adult brain but contributes to highly specific brain functions—most notably, learning and memory. Thus far, its contribution to other brain functions has been less clear. On page 958 of this issue, Chaker et al. (1) report that in mice, pregnancy elicits transient waves of neurogenesis in specific subsections of the subventricular zone (SVZ), the neurogenic zone that produces new interneurons for the olfactory bulb throughout life. These subsections were barely neurogenic in the absence of pregnancy. Once in the olfactory bulb, the newborn neurons contributed to the recognition of the young mice by smell. The data make a compelling case for how adult neurogenesis in the olfactory bulb contributes to an important brain function beyond learning and memory.

Details

Original languageEnglish
Pages (from-to)881-882
Number of pages2
JournalScience
Volume382
Issue number6673
Publication statusPublished - 24 Nov 2023
Peer-reviewedYes

External IDs

PubMed 37995245
ORCID /0000-0002-5304-4061/work/152544172

Keywords

ASJC Scopus subject areas