Genetic risk classification for adults with AML receiving less-intensive therapies: the 2024 ELN recommendations

Research output: Contribution to journal › Comment/Debate › Contributed › peer-review

Contributors

  • Hartmut Döhner - , Ulm University Medical Center (Author)
  • Courtney D DiNardo - , University of Texas MD Anderson Cancer Center (Author)
  • Frederick R Appelbaum - , University of Washington, Fred Hutchinson Cancer Research Center (Author)
  • Charles Craddock - , University of Warwick, University Hospitals Birmingham NHS Foundation Trust (Author)
  • Hervé Dombret - , Hôpital Saint-Louis (Author)
  • Benjamin L Ebert - , Dana-Farber Cancer Institute (Author)
  • Pierre Fenaux - , Hôpital Saint-Louis (Author)
  • Lucy A Godley - , Northwestern University (Author)
  • Robert P Hasserjian - , Boston Children's Hospital (Author)
  • Richard A Larson - , The University of Chicago (Author)
  • Ross L Levine - , Memorial Sloan-Kettering Cancer Center (Author)
  • Yasushi Miyazaki - , Nagasaki University (Author)
  • Dietger Niederwieser - , University Hospital Leipzig (Author)
  • Gert Ossenkoppele - , Amsterdam University Medical Centers (UMC) (Author)
  • Christoph Röllig - , Department of Internal Medicine I, University Hospital Carl Gustav Carus Dresden (Author)
  • Jorge Sierra - , Hospital de la Santa creu i Sant Pau (Author)
  • Eytan M Stein - , Memorial Sloan-Kettering Cancer Center (Author)
  • Martin S Tallman - , Memorial Sloan-Kettering Cancer Center (Author)
  • Hwei-Fang Tien - , National Taiwan University Hospital (Author)
  • Jianxiang Wang - , Chinese Academy of Medical Sciences, Peking Union Medical College (Author)
  • Agnieszka Wierzbowska - , Medical University of Łódź (Author)
  • Andrew H Wei - , Royal Melbourne Hospital (Author)
  • Bob Löwenberg - , Erasmus University Medical Center (Author)

Abstract

The European LeukemiaNet (ELN) genetic risk classifications were developed based on data from younger adults receiving intensive chemotherapy. Emerging analyses from patients receiving less-intensive therapies prompted a proposal for an ELN genetic risk classification specifically for this patient population.

Details

Original languageEnglish
Pages (from-to)2169-2173
Number of pages5
JournalBlood
Volume144
Issue number21
Publication statusPublished - 21 Nov 2024
Peer-reviewedYes

External IDs

Scopus 85203490901

Keywords

Keywords

  • Humans, Leukemia, Myeloid, Acute/genetics, Adult, Risk Assessment, Genetic Predisposition to Disease, Risk Factors