Gel or Die: Phase Separation as a Survival Strategy

Research output: Contribution to journalShort survey/ReviewContributedpeer-review

Contributors

  • Sonja Kroschwald - , Max Planck Institute of Molecular Cell Biology and Genetics (Author)
  • Simon Alberti - , Max Planck Institute of Molecular Cell Biology and Genetics (Author)

Abstract

Stress conditions trigger protein assembly by demixing from the cytoplasm, but the biological significance is still unclear. In this issue of Cell, Riback et al. report that the yeast poly(A)-binding protein 1 (Pab1) is a phase-separating stress sensor that boosts organismal fitness under physiological stress conditions.

Details

Original languageEnglish
Pages (from-to)947-948
Number of pages2
JournalCell
Volume168
Issue number6
Publication statusPublished - 9 Mar 2017
Peer-reviewedYes
Externally publishedYes

External IDs

PubMed 28283065
ORCID /0000-0003-4017-6505/work/142253868

Keywords