Furfuryl- and Maleimido Polysaccharides: Synthetic Strategies Toward Functional Biomaterials

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Thomas Elschner - , Friedrich Schiller University Jena (Author)
  • Franziska Obst - , Leibniz Institute of Polymer Research Dresden (Author)
  • Thomas Heinze - , Friedrich Schiller University Jena (Author)

Abstract

In context with facile and efficient syntheses of functional polymeric materials, the combination of polysaccharides and functional moieties based on renewable resources is a sustainable and valuable approach. This review presents alternatives to prominent click reactions utilizing biopolymer derivatives with furfuryl and maleimide groups. On the one hand, the cross-linking by Diels-Alder reaction of these polymers enables the synthesis of novel materials in the fields of self-healing polymers, tissue engineering, and drug delivery. On the other hand, thiol-ene click reactions allow their conjugation to complex (bio)molecules. Different synthetic strategies are reviewed and the applicability of functional materials is evaluated.

Details

Original languageEnglish
Article number1800258
Number of pages15
JournalMacromolecular bioscience
Volume18
Issue number11
Publication statusPublished - Nov 2018
Peer-reviewedYes
Externally publishedYes

External IDs

Scopus 85054186315

Keywords

Sustainable Development Goals

Keywords

  • biomaterials, furoates, maleimides, polysaccharides, syntheses, DIELS-ALDER REACTION, CONTROLLED DRUG-RELEASE, CLICK CHEMISTRY, CELLULOSE FUROATE, CROSS-LINKING, BIOLOGICAL-ACTIVITY, DEXTRAN ESTERS, FILM FORMATION, HYDROGELS, POLYMERS