Forward Planning in a Population-Based Alcohol Use Disorder Sample

Research output: Contribution to journalResearch articleContributedpeer-review

Abstract

BACKGROUND: Etiological theories of addictive behaviour postulate a key role for decision-making mechanisms. However, current research is lacking compelling computational models for decision-making in multistep forward planning scenarios to identify underlying mechanisms and make derived hypotheses testable.

METHODS: We used a recently developed planning task and computational model to investigate performance, planning time and inferred forward planning parameters like planning depth and decision noise in 30 individuals diagnosed with mostly mild-to-moderate alcohol use disorder (AUD) relative to 32 healthy control participants, both sampled from the general population.

RESULTS: Contrary to our hypothesis, we did not observe reduced planning depth in participants with AUD but found that participants with AUD showed a higher performance in the planning task. Group differences could be explained by planning time and general cognitive performance. Importantly, participants with AUD invested more time for planning, showed a higher correlation of planning depth with incentive value and showed lower response noise, potentially indicative of higher choice consistency.

CONCLUSION: The significant differences in planning time, moderation of planning depth by incentive value and choice consistency may reflect higher motivation and willingness to exert effort among participants with AUD compared to healthy controls. Overall, our findings do not support the notion that mild-to-moderate alcohol use disorder is associated with impairments in forward planning across multiple steps.

Details

Original languageEnglish
Article numbere70072
JournalAddiction biology
Volume30
Issue number8
Publication statusPublished - Aug 2025
Peer-reviewedYes

External IDs

PubMedCentral PMC12356142
Scopus 105013335547
ORCID /0000-0002-2840-8791/work/197962061
ORCID /0000-0001-8761-984X/work/197964853
ORCID /0000-0001-5398-5569/work/197964944

Keywords

Keywords

  • Humans, Male, Female, Adult, Alcoholism/psychology, Decision Making, Middle Aged, Motivation, Case-Control Studies, Young Adult